High hybridization signal was found in the cortical nucleus of the amygdala, piriform and enthorinal cortex, claustrum, olfactory tract, habenula, CA3 hippocampal subregion, endopiriform nucleus, medial mammillary nucleus of the hypothalamus and some nucleus of the brainstem and spinal cord such as motor cranial nerve nuclei, red nucleus, and pontine nuclei is lasix hard on the kidneys I specifically avoided metoprolol and diltiazem IV pushes because I did not want to do anything permanent or drastic